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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO4
All Species:
26.97
Human Site:
Y394
Identified Species:
45.64
UniProt:
Q9GZR2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZR2
NP_065118.2
422
46672
Y394
A
Q
A
A
M
R
L
Y
V
M
V
K
K
E
W
Chimpanzee
Pan troglodytes
XP_528522
404
44489
Y376
A
Q
A
A
M
R
L
Y
V
M
V
K
K
E
W
Rhesus Macaque
Macaca mulatta
XP_001101121
422
46500
Y394
A
Q
A
A
M
R
L
Y
I
M
V
K
K
E
W
Dog
Lupus familis
XP_548392
428
46939
Y396
A
Q
A
A
M
R
L
Y
I
L
V
K
K
E
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAQ4
432
47580
Y404
A
Q
A
A
M
R
L
Y
V
M
V
K
R
E
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508485
438
48720
L382
V
K
S
G
R
P
S
L
K
L
L
C
E
K
L
Chicken
Gallus gallus
XP_001236410
416
45873
L366
A
R
P
S
L
K
L
L
C
D
R
L
L
D
V
Frog
Xenopus laevis
Q91560
421
46679
Y385
A
Q
A
A
M
R
L
Y
T
M
E
K
K
S
W
Zebra Danio
Brachydanio rerio
XP_002665913
418
47625
Y384
A
Q
A
T
M
R
L
Y
T
M
V
R
K
Q
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396691
278
32474
S251
E
I
Q
T
G
E
H
S
S
I
E
D
A
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794891
360
40175
V320
L
A
K
T
V
L
G
V
T
V
Q
E
G
E
H
Poplar Tree
Populus trichocarpa
XP_002300407
274
31114
R247
I
R
D
Q
M
R
L
R
Q
K
Q
N
K
R
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
S262
I
Q
E
G
E
H
S
S
V
E
D
A
R
A
T
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
F367
A
R
V
A
M
L
L
F
R
K
E
K
H
G
F
Conservation
Percent
Protein Identity:
100
94.3
93.1
68.4
N.A.
67.5
N.A.
N.A.
55.7
49
50.7
45
N.A.
N.A.
34.1
N.A.
35.7
Protein Similarity:
100
95.5
95.9
77.3
N.A.
77.5
N.A.
N.A.
68
63.2
67.3
60.9
N.A.
N.A.
47.3
N.A.
53
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
N.A.
N.A.
0
13.3
80
73.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
40
46.6
80
86.6
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
32.2
N.A.
N.A.
N.A.
28.6
26.7
Protein Similarity:
45
N.A.
N.A.
N.A.
43.8
47.6
P-Site Identity:
26.6
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
20
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
8
50
50
0
0
0
0
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
8
8
8
0
8
0
% D
% Glu:
8
0
8
0
8
8
0
0
0
8
22
8
8
43
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
15
8
0
8
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
8
% H
% Ile:
15
8
0
0
0
0
0
0
15
8
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
8
0
0
8
15
0
50
50
8
0
% K
% Leu:
8
0
0
0
8
15
72
15
0
15
8
8
8
0
8
% L
% Met:
0
0
0
0
65
0
0
0
0
43
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
58
8
8
0
0
0
0
8
0
15
0
0
8
0
% Q
% Arg:
0
22
0
0
8
58
0
8
8
0
8
8
15
15
0
% R
% Ser:
0
0
8
8
0
0
15
15
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
22
0
0
0
0
22
0
0
0
0
0
8
% T
% Val:
8
0
8
0
8
0
0
8
29
8
43
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _